![]() Due to HBV infection high related morbidity and mortality the global disease burden is important. Patients with chronic HBV infection have risk of greater than 100-fold of developing HCC as compared with non-carriers. It has been reported that chronic viral infection HBV (50%-55%) and HCV (25%-30%) is the cause of 75%-80% of global HCC patients. Each year more than 500000 new HCC cases with an age-adjusted incidence of 5.5-14.00 populations worldwide are diagnosed. Regions where HBV is hyperendemic like those in East Asia and sub-Saharan most of the carriers of chronic hepatitis B virus develop HCC. HCC is the fifth most common global health problem, and the third leading cause of cancer-related death. It was estimated that 350 million individuals with chronic HBV infection had 15%-25% risk or chances of dying due to HBV-related advanced liver diseases, which includes Hepatocellular carcinoma (HCC) and decompensated cirrhosis. A policy earmarked to combat this virus in Jharkhand is hereby solicited. Viral load is a risk factor for cirrhosis and hepatocellular carcinoma. ![]() 1.1 × 10 8.Ĭonclusion: There was a high occurrence of viral titre as well as suspected core mutants in the population studied. Results: 366 number of patients were tested from 2013 to 2015. ![]() The COBAS Amplicor automated Analyzer (PCR based) was used to assay the virus quantitatively. Method: Variables included socio demographics like age, sex, occupation, history of vaccination, surgery, IVDU.etc. Objectives: This study was carried out to determine the pattern of HBV viral load levels of patients in Jharkhand. HBV infected patients tend to have high HBV DNA levels, and severe liver disease. Treatment reduces viral load to undetectable levels. However, widespread use of assays is still hampered due to the high cost.
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